TABLE 2.

Predictors included in the eight ESCC prediction models

Predictors	Yokoyama T (2008) 16	Etemadi A (2012) 17	Chang, (2013) 18	Wang QL (2019) 11	Chen W (2021) 23	Shen Y (2021) 20	Yang X (2021) 21	Wang QL (2021) 24
Demographic and social economic status
Age		•	•	•	•	•		•
Sex			•	•	•	•	•	•
Ethnicity		•
Education		•		•		•	•
Marital status		•
Living with a partner/place of residents during childhood				•
Family wealth score							•
Lifestyle
Cigarette smoking	•	•	•	•	•	•	•	•
Alcohol consumption	•		•	•		•	•	•
Frequency of green‐yellow vegetables	•
Frequency of fruits	•				•	•
Frequency of salty food					•	•
Frequency of hot food						•
Opium use		•
Tea temperature		•					•
Water source		•
Oral hygiene
Oral health/Frequency of brushing tooth		•					•
Missing and filled teeth number							•
Disease history and symptoms
Disease history of esophagitis or peptic ulcer					•
Retrosternal pain, back pain, or neck pain					•
Physical examination
BMI/Adult height							•	•
Family history
Esophageal cancer/Upper gastrointestinal cancer		•			•		•
Genetics
SNPs			•
ALDH2 with alcohol consumption	•
SNPs with alcohol consumption			•

Abbreviations: ALDH2, aldehyde dehydrogenase‐2; BMI, body mass index; ESCC, esophageal squamous cell carcinoma; SNPs, single nucleotide polymorphisms.

• indicated predictors in the ESCC prediction models.