TABLE 4.
Drugs can be potentially used in glioma treatment
| Rank | Cmap name | Mean | Enrichment | p value | Specificity |
|---|---|---|---|---|---|
| 1 | anisomycin | −0.685 | −0.942 | 0 | 0.0254 |
| 2 | puromycin | −0.643 | −0.914 | 0.00010 | 0.0299 |
| 3 | 16‐phenyltetranorprostaglandin E2 | −0.596 | −0.905 | 0.00014 | 0 |
| 4 | 5182598 | −0.744 | −0.978 | 0.00107 | 0.0126 |
| 5 | sulfadoxine | −0.667 | −0.905 | 0.00162 | 0 |
| 6 | NU‐1025 | −0.529 | −0.908 | 0.01708 | 0.0161 |
The values of mean and enrichment were the indicators to measure the effectiveness of drugs, and the absolute value was positively correlated with the therapeutic effect of drugs, while the negative value represented its inhibitory effect on tumorigenesis.