Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 10;5(17):3478–3491. doi: 10.1182/bloodadvances.2021004404

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by The American Society of Hematology

PMC Copyright notice

Figure 4. — Recombinant human ADAMTS13 and plasma transfusion reduce the deranged ADAMTS13-VWF axis, associated with decreased VWF-platelet thrombi in the lung. Data are shown as boxplots with range. (A-E) Before trauma (T = 0) and 6 hours post-trauma, samples were analyzed for different measures, including VWF antigen (A), rat ADAMTS13 antigen (B), human ADAMTS13 antigen (C), HMW VWF multimers (D), and platelet counts (E). (F) At termination, the lung was assessed for VWF-platelet microthrombi. (G-I) Images (original magnification ×400) of the lung for the assessment of VWF (blue), CD41 + platelets (red), and microthrombi (purple). The arrow in (G) points towards a microthrombus. *P < .05, **P < .01, and ***P < .001 between groups; #P < .05 within groups.