Table 1.

Blood parameters of the patient with Raynaud's phenomenon after COVID-19 vaccination

Parameter, units	Patient's value	Reference range
RBC, T/L	4.7	3.8–5.2
WBC, g/L	6.96	4.0–10.0
Platelet count, g/L	171	150–350
Creatinine, mg/dL	0.70	0.50–0.90
AST, U/L	13	<35
ALT, U/L	12	<35
GGT, U/L	14	<40
Alkaline phosphatase, U/L	55	35–105
LDH, U/L	151	<250
CRP, mg/dL	<0.03	<0.5
D-dimer, µg/mL	0.30	<0.5
Fibrinogen, mg/dL	237	200–400
Prothrombin time, %	109	75–130
aPTT, s	28.9	27.0–41.0
TT, s	15.6	<21
Plasminogen activity, %	104	65–200
Heparin/platelet factor 4 complex (IgG) antibodies (optical density)	Negative (0.02)	Negative (<0.51)
Cryofibrinogen	Negative	Negative
Cryoglobulin	Negative	Negative
ANA	Negative	<1:80
Anti-dsDNA antibodies, IU/mL	<0.6	<10
ENA subsets (SSA [Ro], SSB [La], SCL-70, SM, u1RNP, Jo-1, centromer-B, cardiolipin IgG, cardiolipin IgM, beta-2-glycoprotein IgG, beta-2-glycoprotein IgM)	Negative	Negative
IgG, mg/dL	874	700–1600
IgA, mg/dL	92	70–400
IgM, mg/dL	131	40–230
C3c, mg/dL	92	90–180
C4, mg/dL	16.4	10–40
CH50, U/mL	>60	31.6–57.6
Total protein, g/L	69.6	64–83
Albumin, g/L	49.4	35–52
Alpha-1 globulin, %	4.0	2.9–4.9
Alpha-2 globulin, %	8.7	7.1–11.8
Beta-1 globulin, %	5.7	4.7–7.2
Beta-2 globulin, %	3.8	3.2–6.5
Gamma globulin, %	12.5	11.1–18.8
Paraprotein	Negative	Negative
TSH, µIU/mL	1.60	0.27–4.2
Free T3, pg/mL	3.28	2.15–4.12
Free T4, ng/dL	1.21	0.76–1.66

RBC, red blood cells; WBC, white blood cells; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transpeptidase; LDH, lactic acid dehydrogenase; CRP, C-reactive protein; aPTT, activated partial thromboplastin time; TT, thrombin time; ANA, antinuclear antibodies; TSH, thyroid-stimulating hormone; free t3, free triiodothyronine; free T4, free thyroxine.