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. 2020 Dec 10;2:601541. doi: 10.3389/fgeed.2020.601541

Table 1.

Panel of DNA repair factors assessed in this study.

DNA RFs Description
CtIPE/CtIPDE T847E mutant acts as a CDK- mediated phosphomimetic.; S249D mutant increases BRCA2 recruitment to DSB (Orthwein et al., 2015)
PALB2KR KR mutation in the BRCA1 binding pocket allows for PALB2/BRCA1 binding irrespective of cell cycle (Orthwein et al., 2015)
i53 “Inhibitor of 53BP1” is an ubiquitin variant that binds to 53BP1 and prevents its accumulation at a DSB (Canny et al., 2018)
RAD52 Improves SSTR (Paulsen et al., 2017)
dn53BP1 Dominant negative form of 53BP1; inhibits NHEJ (Paulsen et al., 2017)