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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Brain Behav Immun. 2021 Mar 9;95:122–141. doi: 10.1016/j.bbi.2021.03.002

Figure 4. Open-field activity monitoring test.

Figure 4.

The overall activity of mice in an open field arena was monitored one day after the BLG challenge. The first 4 min of the test were analyzed to assess differences in the number of entries to the center area (A), total time spent in the center (B), and the duration of each entry to the center (C). In addition, the numbers of fecal pellets excreted during the test were counted as an alternative measure of anxiety-like behavior (D). Sham mice (open bars with open triangles); BLG mice (striped bars with filled diamonds); male C57BL/6J (blue); male BALB/cJ (red); female C57BL/6J (green); female BALB/cJ (orange). Bars indicate group average values ± SEM (n = 8–10 per group), two-way ANOVA.