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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Brain Behav Immun. 2021 Mar 9;95:122–141. doi: 10.1016/j.bbi.2021.03.002

Figure 6. Cross maze test.

Figure 6.

Spatial memory of mice was tested using a cross maze one day after the BLG challenge. Mice were allowed to explore the maze freely for 12 min, and the numbers of successful sequence alternations (A) and the total number of entries into the arms (B) were recorded manually from video files. The number of successful alternations of arm entries made by each mouse was converted to percent alternations using the equation described in the Materials and Methods section. Mice that did not leave the starting position were removed from the final analysis. Sham mice (open bars with open triangles); BLG mice (striped bars with filled diamonds); male C57BL/6J (blue); male BALB/cJ (red); female C57BL/6J (green); female BALB/cJ (orange). Bars indicate group average values ± SEM (n = 5–10 per group), two-way ANOVA.