TABLE 1.

Summary of chart review patients

Pretest EORTC category	No. of:			No. (%) positive by:		Culture vs PCR P valueb
	Unique patientsa	Patients with pretest antifungal exposure	Paired specimens	Culture	PCR
All	52	43	54	29 (53.7)	36 (66.7)	0.238
Proven IFI	28	23	28	22 (78.6)	25 (89.3)	0.844
Probable IFI	9	7	10	5 (50.0)	7 (70.0)	0.726
Possible IFI	11	11	11	0 (0.0)	1 (9.1)	NDd
Not applicablec	5	1	5	2 (40.0)	3 (60.0)	ND

^aOne patient had parallel PCR and culture performed three times with >3 weeks between each sampling, and each encounter was included as a single unique patient for overall counts, but testing was counted twice as “probable” and once as “proven” IFI based on chart review.

^bFisher’s exact test.

^cOne patient to whom EORTC criteria were not applicable had HIV and a CD4 count of 14 cells/μl, and pretest amphotericin B had a true positive detection of A. fumigatus by PCR only; all other results for patients in this category were clinically thought to reflect bystanders/colonizers.

^dND, not determined.