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. 2021 Sep 21;99(10):skab268. doi: 10.1093/jas/skab268

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Figure 7. — Sodium oxalate-induced disruption in barrier function of MDCK cells is revered by treatment of SB216763. (A) TEER measurement of MDCK monolayer treated with NaOx in the presence or absence of SB216732. (B) Evaluation of paracellular permeability by FITC-Dextran assay. (C and D) Western blot analysis of tight junction proteins (claudin-1, occluding, ZO-1, ZO-2, and ZO-3) in MDCK cells exposed to NaOx, SB216763, or NaOx in combination with SB216763 (n = 3). Means with no common letters indicate significant difference (P < 0.05). Abbreviations: FITC, fluorescein isothiocyanate; MDCK, Mardin–Darby canine kidney; NaOx, sodium oxalate; TEER, transepithelial electrical resistance; ZO, zonula occluden.