Table 1.
Main methodologies described in the selected papers to evaluate cancer and occupational exposure to pesticides
| Methodologies | Classification (types) | Number of studies N (%) |
|---|---|---|
| Qualitative methods | Questionnaire | 24 (38.7%) |
| MRADC | 2 (3.1%) | |
| Molecular biology | PCR | 2 (3.1%) |
| SNP genotyping | 2 (3.1%) | |
| Methylation profile | 3 (4.8%) | |
| Cytogenetic tests | Micronucleus test | 5 (7.9%) |
| Comet assay | 3 (4.8%) | |
| Fluorescent in situ hybridization (FISH) | 1 (1.6%) | |
| Hematological tests | Complete blood count (CBC) | 4 (6.4%) |
| Biochemical tests | Acetylcholinesterase quantification | 3 (4.8%) |
| Other biochemical tests | 4 (6.4%) | |
| Determination of pesticides residues (in saliva, blood, urine) | Spectrometry | 3 (4.8%) |
| Chromatography | 4 (6.4%) | |
| Immunological analyses | Flow cytometry | 1 (1.6%) |
| Immunofluorescence staining | 1 (1.6.%) |
MRADC medical record analysis and death certificate, PCR polymerase chain reaction, SNP single nucleotide polymorphism