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. Author manuscript; available in PMC: 2021 Oct 19.
Published in final edited form as: Lancet Planet Health. 2021 Oct;5(10):e689–e697. doi: 10.1016/S2542-5196(21)00204-7

Table 3:

Main study results, including E values

Risk difference (95% CI)* Attributable increase in number of cases (95% CI) E value (multiplicative scale)
Main analyses
PM2·5, μg/m3 0·073% (0·071–0·076) 11 540 (11 087–11 992) 1·062
NO2, ppb 0·003% (0·003–0·004) 1176 (998–1353) 1·013
O3, ppb 0·081% (0·080–0·083) 15 115 (14 896–15 333) 1·066
Medicaid eligible
PM2·5, μg/m3 0·113% (0·103–0·124) 2032 (1843–2222) 1·079
NO2, ppb 0·012% (0·010–0·014) 540 (454–627) 1·024
O3, ppb 0·117% (0·113–0·120) 2741 (2653–2828) 1·080
Not Medicaid eligible
PM2·5, μg/m3 0·067% (0·064–0·070) 9382 (8975–9789) 1·060
NO2, ppb 0·004% (0·004–0·005) 1332 (1175–1489) 1·014
O3, ppb 0·073% (0·072–0·075) 11 924 (11 724–12 123) 1·062
Male individuals
PM2·5, μg/m3 0·086% (0·082–0·091) 6080 (5768–6393) 1·068
NO2, ppb 0·003% (0·002–0·004) 415 (296–534) 1·011
O3, ppb 0·083% (0·081–0·085) 6701 (6553–6850) 1·067
Female individuals
PM2·5, μg/m3 0·064% (0·060–0·068) 5544 (5218–5871) 1·058
NO2, ppb 0·003% (0·003–0·004) 669 (538–800) 1·013
O3, ppb 0·080% (0·079–0·082) 8414 (8254–8574) 1·065
Black individuals
PM2·5, μg/m3 0·058% (0·044–0·073) 525 (392–658) 1·055
NO2, ppb 0·018% (0·016–0·020) 542 (478–607) 1·030
O3, ppb 0·104% (0·100–0·109) 1766 (1693–1838) 1·075
White individuals
PM2·5, μg/m3 0·076% (0·073–0·079) 10 505 (10 069–10 940) 1·064
NO2, ppb 0·002% (0·002–0·003) 747 (580–913) 1·011
O3, ppb 0·079% (0·078–0·081) 12 430 (12 221–12 640) 1·065
Older than 64 years and younger than 75 years
PM2·5, μg/m3 0·034% (0·032–0·037) 3608 (3334–3881) 1·042
NO2, ppb 0·003% (0·003–0·004) 647 (555–738) 1·013
O3, ppb 0·043% (0·042–0·044) 4767 (4643–4891) 1·047
75 years or older and younger than 85 years
PM2·5, μg/m3 0·106% (0·099–0·113) 3984 (3722–4247) 1·076
NO2, ppb 0·004% (0·003–0·005) 518 (406–630) 1·015
O3, ppb 0·121% (0·119–0·124) 6369 (6237–6501) 1·082
85 years of age and older
PM2·5, μg/m3 0·216% (0·199–0·234) 3178 (2918–3438) 1·112
NO2, ppb 0·005% (0·003–0·008) 251 (142–360) 1·016
O3, ppb 0·234% (0·228–0·240) 5039 (4911–5168) 1·117
1st-quartile median household income
PM2·5, μg/m3 0·185% (0·179–0·191) 7263 (7018–7508) 1·103
NO2, ppb 0·010% (0·009–0·011) 911 (814–1008) 1·022
O3, ppb 0·117% (0·114–0·119) 5413 (5293–5533) 1·080
2nd-quartile median household income
PM2·5, μg/m3 0·041% (0·035–0·046) 1601 (1376–1825) 1·046
NO2, ppb 0·009% (0·007–0·010) 759 (662–857) 1·020
O3, ppb 0·077% (0·074–0·079) 3573 (3458–3688) 1·064
3rd-quartile median household income
PM2·5, μg/m3 0·045% (0·039–0·050) 1751 (1534–1968) 1·048
NO2, ppb 0·001% (0–0·002) NA 1·006
O3, ppb 0·086% (0·083–0·088) 3984 (3867–4102) 1·068
4th-quartile median household income
PM2·5, μg/m3 0·012% (0·006–0·018) 474 (244–703) 1·024
NO2, ppb −0·006% (−0·007 to −0·005) NA 1·017
O3, ppb 0·051% (0·048–0·053) 2357 (2247–2468) 1·051
1st-quartile population density
PM2·5, μg/m3 0·074% (0·068–0·080) 2898 (2656–3141) 1·063
NO2, ppb 0·009% (0·008–0·011) 827 (704–949) 1·021
O3, ppb 0·063% (0·061–0·066) 2946 (2816–3076) 1·058
2nd-quartile population density
PM2·5, μg/m3 0·073% (0·066–0·080) 2849 (2575–3123) 1·062
NO2, ppb 0·012% (0·010–0·013) 1057 (933–1181) 1·024
O3, ppb 0·050% (0·048–0·053) 2338 (2208–2468) 1·051
3rd-quartile population density
PM2·5, μg/m3 0·034% (0·027–0·041) 1328 (1048–1609) 1·042
NO2, ppb 0% (−0·002 to 0·001) NA 1·004
O3, ppb 0·077% (0·075–0·080) 3597 (3482–3711) 1·064
4th-quartile population density
PM2·5, μg/m3 0·050% (0·044–0·057) 1979 (1712–2246) 1·051
NO2, ppb −0·007% (−0·008 to −0·006) NA 1·019
O3, ppb 0·118% (0·115–0·121) 5491 (5362–5620) 1·081
1st-quartile Hispanic percentage
PM2·5, μg/m3 0·066% (0·059–0·073) 2591 (2310–2872) 1·059
NO2, ppb 0·009% (0·007–0·010) 771 (652–889) 1·021
O3, ppb 0·117% (0·114–0·120) 5419 (5276–5561) 1·080
2nd-quartile Hispanic percentage
PM2·5, μg/m3 0·057% (0·050–0·063) 2224 (1955–2492) 1·054
NO2, ppb 0·001% (0–0·002) NA 1·007
O3, ppb 0·087% (0·084–0·090) 4033 (3895–4172) 1·068
3rd-quartile Hispanic percentage
PM2·5, μg/m3 0·062% (0·056–0·069) 2454 (2209–2699) 1·057
NO2, ppb 0·005% (0·004–0·006) 432 (337–527) 1·015
O3, ppb 0·054% (0·051–0·056) 2495 (2379–2611) 1·053
4th-quartile Hispanic percentage
PM2·5, μg/m3 0·075% (0·070–0·080) 2950 (2739–3160) 1·063
NO2, ppb 0·004% (0·003–0·005) 313 (222–405) 1·013
O3, ppb 0·071% (0·069–0·073) 3280 (3191–3368) 1·061

PM2·5=particulate matter less than 2·5 μg/m³ in diameter. NA=not applicable. NO2=nitrogen dioxide. O3=ozone.

*

Per one-unit increase in pollutants per year (1 μg/m³ for PM2·5 and 1 ppb for NO2 and O3).

Covariates included other pollutants, warm-season and cold-season temperatures, year, age, race, sex, Medicaid eligibility, region of residence, distance to nearest hospital, percentage of people who had an A1c exam, percentage of people who had an ambulatory-care visit, percentage of people who had a cholesterol exam, percentage of people who had an eye exam, percentage of women who had a mammogram, percentage of the population who are Black, percentage of the population who are Hispanic, population density per square mile, percentage of the population living below the poverty line, percentage of the housing occupied by the owners, median value of housing occupied by the owners, median household income, percentage of the population who did not graduate from high school, mean body-mass index, rate of smoking, and rate of lung cancer.

Negative values on a probability scale are not logical. As such, attributable number of cases were not calculated.