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. 2021 Oct 19;16(10):e0258800. doi: 10.1371/journal.pone.0258800

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© 2021 Al Za’abi et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Photomicrograph of renal tissues (Bar = 100μm, H&E stain): (A; control group) showing normal renal tissue with intact glomeruli and renal tubules (Score 0); (B; adenine group) showing marked renal tubular necrosis with pyknotic nuclei (arrowheads), cystic dilatation of multiple renal tubules (asterisks), marked basophilia, and dilatation of bowman’s capsule (arrow) (Score 4); (C; streptozotocin group) showing moderate basophilia with cystic dilation of few renal tubules (asterisk) and focal aggregates of mononuclear cells (arrowhead) (Score 2); (D; adenine + streptozotocin group) showing marked basophilia, renal tubular necrosis (arrowheads), cystic dilatation of multiple renal tubules (asterisks), and cellular casts in multiple tubules (arrow) (Score 4); (E; flaxseed group) showing histologically normal renal tubules with the exception of few dilated tubules (asterisk) (Score 1); (F; adenine + flaxseed group) showing tubular basophilia, tubular dilatations (asterisks) and cellular casts (arrow) (Score 3); (G; streptozotocin + flaxseed group) showing normal histological structures of the majority of the renal tubules with intact glomeruli (Score 1); (H; adenine + streptozotocin + flaxseed group) showing normal histological structures of the renal tubules with intact glomeruli (Score 0).