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. 2021 Oct 19;18(10):e1003818. doi: 10.1371/journal.pmed.1003818

Table 3. Model projections of the HCV-related morbidity and mortality due to the SQ and EL scenarios over 2018 to 2030.

DALYs are discounted at a rate of 3.5% per annum. The values represent the median and 95% UIs across 1,151 model fits.

2030 Estimates SQ EL
People living with hepatitis C in 2030 (millions) Total 8.99 (8.12–10.00) 1.21 (1.05–1.39)
Averted -- 7.78 (7.03–8.66)
% Reduction -- 86.5% (85.5%–87.4%)
Cumulative hepatitis C–related deaths 2018–2030 Total 1,153,000 (811,000–1,678,000) 821,000 (589,000–1,105,000)
Averted -- 333,000 (219,000–509,000)
% Reduction -- 28.9% (25.2%–33.1%)
Total DALYs* 2018–2030 (millions) Total 24.06 (18.58–31.42) 18.53 (14.61–23.43)
Averted -- 5.57 (3.80–8.22)
% Reduction -- 23.2% (19.6%–27.5%)

*Total DALYs = Years Lived with Disability (YLD) + Years of Life Lost (YLL).

DALY, disability-adjusted life year; EL, elimination; HCV, hepatitis C virus; SQ, status quo; UI, uncertainty interval.