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. 2021 Oct 5;11:739660. doi: 10.3389/fonc.2021.739660

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Copyright © 2021 Liu, Huang, Zhu, He, Zhang, Lei, Xuan, Xiao, Li, Zhou and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significant correlation between expression levels of TRiC subunits in HCC. (A) Pearson correlation analysis of the TRiC subunits in HCC (from cBioPortal). (B) Efficiencies of CCT overexpression and knockdown in SK-HEP1 cells following plasmid and siRNA transfection, respectively, as confirmed by western blotting (left) and qPCR (right). (C) CCT5 overexpression and knockdown-induced changes in the expression of other subunits were confirmed by qPCR. *p < 0.05, **p < 0.01, ***p < 0.001. ns, no significance.