. Author manuscript; available in PMC: 2021 Oct 19.

Published in final edited form as: Curr Opin Lipidol. 2020 Apr;31(2):71–79. doi: 10.1097/MOL.0000000000000673

TABLE 2.

Percent activation of synthetic peptide LCAT activators relative to apoA-I

	Percent activity (compared to full-length apoA-I)
Peptide	Egg PC (Vesicular)	Egg PC (Discoidal)	DMPC
ApoA-I	100	100	100^*
LAP-20			50
AP	18
GALA			85
18A	18	30
37pA	Up to 100^**	30
[Glu^1,8Leu^11,17]18A	34		460
ESP24218	93 – 125

35% as active as apo A-l in egg PC vesicular assay system

^**

Biphasic; low affinity compared to apoA-I (ref. 53).

Adapted from Reference (43)