Figure 1.
CircRNA_0003962 is downregulated in spinal cord tissues of SCI rats. A-B, circRNA microarray was performed based on 3 spinal cord tissues of SCI and sham-operated rats for volcano plot (a) and heatmap (b) mapping; C, RT-qPCR detection of the top ten differentially expressed circRNAs in spinal cord tissues at T8 from sham-operated and SCI rats on the 56th day after surgery (n = 6); D, The host gene for circ_0003962 and its conservation in Homo sapiens as well as in Rattus norvigecus; E, RT-qPCR detection of circTYW1 expression in OGD-treated PC12 cells. Data were presented as the mean ± SD. Unpaired t test was used for statistical analysis. All experiments were repeated at least three times, and each experiment was performed in triplicate. **p < 0.01 vs sham-operated rats or PC12 cells treated with normal condition