Figure 2.

Overexpression of circTYW1 promotes neurological recovery in SCI rats. A, the time course of the experiment; B, expression of circTYW1 in spinal cord tissues of rats by RT-qPCR; C, BBB score assessment of recovery of locomotion in rats after SCI surgery; D, Nissl staining for neuronal activity in rat spinal cord tissues; E, TUNEL staining for the proportion of apoptotic neurons in rat spinal cord tissues; F, FJC staining for the proportion of neurons damaged in rat spinal cord tissues; G, staining intensity of Capsase-3 in rat spinal cord tissues by immunohistochemistry. n = 6. Data were presented as the mean ± SD. One-way ANOVA with Tukey’s post-hoc test was used for statistical analysis. **p < 0.01 vs SCI rats injected with Lv-NC