Table 1.

Chronology of M. abscessus isolation from respiratory samples from patient C, clinical disease parameters, and antibiotic treatment

Months after diagnosis	Isolate	Colony morphology	BMI	FEV11	Administered antibiotics
1	09–13-3	smooth	15,9	77,9
	09–13-7	smooth
5	23–13-1	smooth	15,9	77,0	Cotrimoxazole, Clarithromycin, Minocycline, Moxifloxacin (oral)
	23–13-4	smooth
10	30–14-1	smooth	15,0	65,0	Clarithromycin, Minocycline oral Amikacin (nebulized)
	30–14-2	smooth
18	40–14-1	rough	16,2	68,0	Amikacin (iv) Azithromycin, Linezolid (oral)
	40–14-3	smooth
	40–14-8	smooth
26	58–15-2	rough	14,8	53,0
	58–15-4	rough
	58–15-6	smooth
	58–15-9	smooth
32	65–16-13	smooth	16,0	64,0	Amikacin, Cefoxitin (iv) Ciprofloxacin, Minocycline (oral)
	65–16-15	smooth
	65–16-17	rough
	65–16-20	rough
34	74–16-1	smooth	16,0	64,0	Cefoxitin (iv) Ciprofloxacin, Clofazimine, Azithromycin (oral)
	74–16-2	smooth
	74–16-3	rough
	74–16-4	rough
36	77–16-4	smooth	16,2	62,0	Cefoxitin (iv) Ciprofloxacin, Clofazimine, Azithromycin (oral)
	77–16-7	smooth
38	79–16-1	rough	15,8	47,0	Cefoxitin (iv) Ciprofloxacin, Clofazimine, Azithromycin (oral)
	79–16-4	smooth
	79–16-6	smooth
49	103–17-1	smooth	14,2	41,0	Cefoxitin (iv) Ciprofloxacin, Clofazimine, Azithromycin (oral)
	103–17-3	rough
53	109–17-1	rough	14,9	46,0	Cefoxitin (iv) Ciprofloxacin, Clofazimine, Azithromycin (oral)
	109–17-3	smooth

BMI: Body mass index; FEV1: Forced expiratory volume per second. ¹% of predicted.