Figure 1. A pictorial representation of the similarities and differences in mechanism, circumstances, and patient base between the three major types of pathogenic sepsis. The best-known mechanisms for each sepsis type are represented, although these molecules and mechanisms are not universal.

CNS: central nervous system; IFN: interferon; IL: interleukin; ICU: intensive care unit; MAP: mitogen-activated protein; ROS: reactive oxygen species; TLR: toll-like receptor; TNF: tumor necrosis factor

Dolin HH, Papadimos TJ, Chen X, Pan ZK: Characterization of pathogenic sepsis etiologies and patient profiles: a novel approach to triage and treatment. Microbiol Insights. 2019, 12:1178636118825081. [19] (Reprinted with permission from SAGE publications).