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The results correspond to the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001 for aged-donor vs. young-donor ASCs, §P<0.05, §§P<0.01 metformin-treated vs. non-treated ASCs. All experiments were performed in duplicate in ASCs isolated from 3 different donors in each group. #P<0.05, ##P<0.01, ###P<0.001 vs. young- or aged-donor ASCs at P3.
