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The heat map of the clinical sample diagnosis with the NESBA. Fluorescent signals produced from E(I)-MB and N(I)-MB at 30 min in response to gRNA of representative, suspicious COVID-19 patients. The heat map results indicate the fluorescent signals from 0 to 300 a.u., determining the final diagnosis decision as (a) positive and (b) negative based on the threshold (background + 5SD).
