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. 2021 Aug 31;41(9):1287–1295. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2021.09.01

1.

胃癌中ELK3表达与各临床病理特征的关系

Relationship between ELK3 expression and clinicopathological characteristics of gastric cancer

Clinicopathological characteristics Low expression(n) High expression(n) P
Gender Male 294 139
Female 161 77 0.9468
Age(year) ≤60 141 74
>60 314 142 0.3964
T stage T1 5 5
T2 166 85
T3 142 91
T4 13 10 0.4538
N stage N0 64 27
N1 156 64
N2 91 48
N3 30 36 0.0014
M stage M0 195 78
M1 16 11 0.1915
AJCC stage Stage Ⅰ 59 29
Stage Ⅱ 115 41
Stage Ⅲ 130 108
Stage Ⅳ 94 66 0.0010
Grade G1 2 0
G2 9 4
G3 16 7 0.6503
Lauren classification Diffuse 162 104
Mixed 255 92
Intestinal 37 15 0.0037
Poor 80 42
Differentiation Moderate 38 43
Well 5 3 0.0297
Adenocarcinoma 27 53
Pathology Mucinous adenocarcinoma 2 6
classification Signet ring cell carcinoma 10 27
Tubular adenocarcinoma 112 39 < 0.0001
Perineural invasion Not 112 47
Yes 57 31 0.3588
Venous invasion Not 86 43
Yes 33 11 0.3029
Lymphovascular Not 52 21
invasion Yes 144 61 0.8736
Margins R0 44 22
R1 4 0 0.1632
MLH1 status Negative 47 17
Positive 162 72 0.5147
TP53 status Negative 85 22
Positive 64 15 0.7905
Microsatellite status MSI 66 21
MSS 9 10 0.0134
Epstein-Barr virus Negative 184 73
Infection Positive 10 8 0.1490