1.
胃癌中ELK3表达与各临床病理特征的关系
Relationship between ELK3 expression and clinicopathological characteristics of gastric cancer
| Clinicopathological characteristics | Low expression(n) | High expression(n) | P | |
| Gender | Male | 294 | 139 | |
| Female | 161 | 77 | 0.9468 | |
| Age(year) | ≤60 | 141 | 74 | |
| >60 | 314 | 142 | 0.3964 | |
| T stage | T1 | 5 | 5 | |
| T2 | 166 | 85 | ||
| T3 | 142 | 91 | ||
| T4 | 13 | 10 | 0.4538 | |
| N stage | N0 | 64 | 27 | |
| N1 | 156 | 64 | ||
| N2 | 91 | 48 | ||
| N3 | 30 | 36 | 0.0014 | |
| M stage | M0 | 195 | 78 | |
| M1 | 16 | 11 | 0.1915 | |
| AJCC stage | Stage Ⅰ | 59 | 29 | |
| Stage Ⅱ | 115 | 41 | ||
| Stage Ⅲ | 130 | 108 | ||
| Stage Ⅳ | 94 | 66 | 0.0010 | |
| Grade | G1 | 2 | 0 | |
| G2 | 9 | 4 | ||
| G3 | 16 | 7 | 0.6503 | |
| Lauren classification | Diffuse | 162 | 104 | |
| Mixed | 255 | 92 | ||
| Intestinal | 37 | 15 | 0.0037 | |
| Poor | 80 | 42 | ||
| Differentiation | Moderate | 38 | 43 | |
| Well | 5 | 3 | 0.0297 | |
| Adenocarcinoma | 27 | 53 | ||
| Pathology | Mucinous adenocarcinoma | 2 | 6 | |
| classification | Signet ring cell carcinoma | 10 | 27 | |
| Tubular adenocarcinoma | 112 | 39 | < 0.0001 | |
| Perineural invasion | Not | 112 | 47 | |
| Yes | 57 | 31 | 0.3588 | |
| Venous invasion | Not | 86 | 43 | |
| Yes | 33 | 11 | 0.3029 | |
| Lymphovascular | Not | 52 | 21 | |
| invasion | Yes | 144 | 61 | 0.8736 |
| Margins | R0 | 44 | 22 | |
| R1 | 4 | 0 | 0.1632 | |
| MLH1 status | Negative | 47 | 17 | |
| Positive | 162 | 72 | 0.5147 | |
| TP53 status | Negative | 85 | 22 | |
| Positive | 64 | 15 | 0.7905 | |
| Microsatellite status | MSI | 66 | 21 | |
| MSS | 9 | 10 | 0.0134 | |
| Epstein-Barr virus | Negative | 184 | 73 | |
| Infection | Positive | 10 | 8 | 0.1490 |