Table 1.
Baseline pre- and postbronchodilator pulmonary function (n = 48)
| Prebronchodilator | Postbronchodilator (Albuterol) | Bronchodilator Effect (Albuterol) | % Increase | |
|---|---|---|---|---|
| FEV1, L | 1.72 ± 0.56 | 1.86 ± 0.58 | 0.14 ± 0.14 | 9.1 ± 9.4% |
| FEV1, % Predicted (19) | 58.6 ± 13.8 | 63.6 ± 13.9 | - | - |
| FVC, L | 3.35 ± 0.89 | 3.56 ± 0.98 | 0.21 ± 0.30 | 6.2 ± 8.8% |
| FVC, % Predicted (19) | 87.1 ± 14.4 | 92.2 ± 15.3 | - | - |
| FEV1/FVC, % (19) | 51.8 ± 11.6 | 53.2 ± 11.4 | - | - |
| TLC, L | 6.15 ± 1.72 | - | - | - |
| TLC, % Predicted (20) | 101 ± 17 | - | - | - |
| FRC, L | 3.55 ± 1.57 | - | - | - |
| FRC, % Predicted | 110.5 ± 39.9 | - | - | - |
| RV, L | 2.68 ± 1.19 | - | - | - |
| RV, % Predicted | 118 ± 45 | - | - | - |
| RV/TLC, % | 42.8 ± 8.9 | - | - | - |
| IC | 2.60 ± 0.66 | - | - | - |
| IC, % Predicted | 98 ± 22 | - | - | - |
| DLCO, mL/min/mmHg | 15.2 ± 4.9 | - | - | - |
| DLCO, % Predicted (21) | 59.3 ± 16.1 | - | - | - |
| CT emphysema, % < LA 950* | 9.09 ± 7.71 | - | - | - |
| CT mean segmental wall thickness, mm* | 3.61 ± 0.47 | - | - | - |
All values, mean ± SD. FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; TLC, total lung capacity; RV, residual volume; DLCO, diffusing capacity of the lung for carbon monoxide. *CT, computed tomography, n = 46 (2 subjects had a recent CT and did not repeat a quantitative CT for the study).