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. Author manuscript; available in PMC: 2022 Feb 12.
Published in final edited form as: Oncogene. 2021 Aug 12;40(41):5984–5992. doi: 10.1038/s41388-021-01972-6

Fig. 5. Deletion of Apc induces tumor immune evasion by induction of PD-L1 in vivo.

Fig. 5.

(A) The representative immunostaining of PD-L1 in colon tissues taken from the indicated group of mice. (B) The percentage of PD-L1-positive colon epithelial cells was determined by flow cytometry in the indicated group of mice. (C) The percentage of dead colon epithelial cells was determined by flow cytometry after co-culture with activated mouse splenic CD8+ T cells in the indicated group of mice. (D) Average numbers of polyps at different size and total that includes all sizes in mice treated with IgG or anti-PD-L1 antibody. The error bar indicates ± SEM. *p<0.05.