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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 Jun 15;13(6):e1732. doi: 10.1002/wnan.1732

FIGURE 1.

FIGURE 1

(a) Methods for dissolution rate assessment of NPs. In vivo dissolution studies are not always feasible. Acellular in vitro tests could reflect the dissolution behavior in blood (en route to target tissues) while cellular in vitro tests could reflect dissolution inside target cells. (b) Dissolution methods to test liposomes (based on 56 publications accessed for 2010-2020). During last decade more than one thousand articles were published illustrating different in vitro dissolution studies for various NDDS. As liposomes are most widely approved NDDS an account was made for them specifically.