Skip to main content
. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: DNA Repair (Amst). 2021 Aug 8;107:103201. doi: 10.1016/j.dnarep.2021.103201

Figure 2: Acetylation of K56 of the H3 histone greatly weakens a network of interactions between DNA and the H3 αN helix as well as the R81 of H2A with the surrounding residues.

Figure 2:

(A) Acetylation of K56 weakens the interactions between the H3 αN helix and the DNA. Best representative structure showing the interactions between the H3 αN helix and the DNA in the left panel; the corresponding hydrogen bond numbers are depicted in the right panel. Details concerning all the hydrogen bond acceptor-donor pairs are listed in Table S1.

(B) Acetylation of K56 dimishes the interactions of H2A R81 and the surrounding residues, Q55 of H3 and G105/V107 from the H2A C-loop. Best representative structure showing the interactions between H2A R81 and the surrouding residues in the left panel; the corresponding hydrogen bond numbers are shown in the right panel. Details concerning all the hydrogen bond acceptor-donor pairs are listed in Table S2.