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Kinetic parameters of the interaction between the SARS-CoV-2 nucleoprotein and the different VHHs
| VHH | Kd (nM) | kon (105 M−1 s−1) | koff (10−4 s−1) |
|---|---|---|---|
| D12-3 | 5.78 ± 1.15 | 13.8 ± 3.1 | 77.2 ± 2.1 |
| E7-2 | 0.206 ± 0.073 | 7.05 ± 2.04 | 1.81 ± 0.56 |
| E10-3 | 24.1 ± 4.0 | 1.49 ± 0.26 | 35.5 ± 7.0 |
| G9-1 | 2.40 ± 0.38 | 5.96 ± 1.27 | 14.0 ± 1.4 |
| H3-3 | 0.902 ± 0.119 | 10.0 ± 0.9 | 9.00 ± 1.09 |
| NTD B6-1 | 46.5 ± 2.6 | 4.24 ± 0.57 | 201 ± 29 |
| NTD E4-3 | 23.8 ± 2.1 | 5.97 ± 0.94 | 140 ± 11 |
