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Evaluation of differentiation markers under JQ1 and ATRA combinatorial treatments in NB cells
(A and B) Gene expression by RT-PCR of TH and MBP in Kelly, SY5Y, and SKNAS cells under the treatment of independent and combinations of JQ1 + ATRA. (C−E) Protein expression analyzed by western blots of TH and ASCL1 in the three cell lines under the treatment of independent and combinations of JQ1 + ATRA. (Data presented as mean ± SEM with n = 3, ∗∗p < 0.01.)
