Table 1.
The univariate analysis for association between FA features in the vascularized retina with development of treatment-requiring ROP (N = 98 eyes).
| FA characteristics | # eyes | Treatment (%) | OR (95% CI) | P valuea (linear trend p valueb) |
|---|---|---|---|---|
| Foveal avascular zone | 0.95 (0.78) | |||
| Absent | 53 | 12 (22.6%) | 1 | |
| Present | 16 | 3 (18.8%) | 0.79 (0.14, 4.49) | |
| Ungradable | 29 | 6 (20.7%) | 0.89 (0.28, 2.84) | |
| Choroidal vascular pattern | 0.16 (0.13) | |||
| Linear | 39 | 12 (30.8%) | 1 | |
| Lobular | 13 | 1 (7.7%) | 0.18 (0.02, 1.66) | |
| Ungradable | 46 | 8 (17.4%) | 0.47 (0.16, 1.36) | |
| Hypofluorescent areas WITH Hyperfluorescence | 0.18 (0.03) | |||
| None | 14 | 1 (7.1%) | 1 | |
| Mild | 19 | 4 (21.1%) | 3.47 (0.31, 38.4) | |
| Moderate | 21 | 5 (23.8%) | 4.06 (0.41, 40.6) | |
| Severe | 11 | 6 (54.6%) | 15.6 (1.52, 160) | |
| Ungradable | 33 | 5 (15.2%) | 2.32 (0.36, 15.1) | |
| Hypofluorescent area WITHOUT Hyperfluorescence | 0.49 (0.22) | |||
| None/mild | 15 | 3 (20.0%) | 1 | |
| Moderate | 33 | 7 (21.2%) | 1.08 (0.24, 4.75) | |
| Severe | 17 | 6 (35.3%) | 2.18 (0.48, 9.86) | |
| Ungradable | 33 | 5 (15.2%) | 0.71 (0.17, 3.01) |
aFor comparison of treatment rate difference across all groups of grading including ungradable, and inter-eye correlation was accounted for by using Generalized estimating equation.
bThe comparison of treatment rate difference across groups excluding ungradable using test of linear trend, and inter-eye correlation was accounted for by using Generalized estimating equation.