Table 2.
43 Up-regulated proteins in Scz organoids (>0.5 Log2FC, p < 0.05).
| Gene Name | Protein Name | Uniprot ID | Log2FC | P-value |
|---|---|---|---|---|
| SLC2A3 | Solute carrier family 2, facilitated glucose transporter member 3 | P11169 | 1.019 | 0.003 |
| GSTA2 | Glutathione S-transferase A2 | P09210 | 0.954 | 0.030 |
| PODXL | Podocalyxin | O00592-2 | 0.939 | 0.000 |
| KRT18 | Keratin, type I cytoskeletal 18 | P05783 | 0.884 | 0.000 |
| AFP | Alpha-fetoprotein | P02771 | 0.868 | 0.027 |
| S100A10 | Protein S100-A10 | P60903 | 0.861 | 0.032 |
| AHSG | Alpha-2-HS-glycoprotein | P02765 | 0.843 | 0.001 |
| APOM | Apolipoprotein M | O95445-2 | 0.771 | 0.002 |
| FGG | Fibrinogen gamma chain | P02679-2 | 0.768 | 0.010 |
| FGB | Fibrinogen beta chain | P02675 | 0.753 | 0.001 |
| FGA | Fibrinogen alpha chain | P02671-2 | 0.749 | 0.008 |
| LIN28A | Protein lin-28 homolog A | Q9H9Z2 | 0.731 | 0.001 |
| SLC9A3R1 | Na(+)/H( + ) exchange regulatory cofactor NHE-RF1 | O14745 | 0.726 | 0.001 |
| APOA1 | Apolipoprotein A-I | P02647 | 0.715 | 0.015 |
| SERPINB9 | Serpin B9 | P50453 | 0.712 | 0.001 |
| SERPINA1 | Alpha-1-antitrypsin | P01009 | 0.705 | 0.009 |
| APOE | Apolipoprotein E | P02649 | 0.698 | 0.006 |
| TF | Serotransferrin | P02787 | 0.687 | 0.005 |
| S100A11 | Protein S100-A11 | P31949 | 0.685 | 0.012 |
| APOC3 | Apolipoprotein C-III | P02656 | 0.678 | 0.027 |
| EPCAM | Epithelial cell adhesion molecule | P16422 | 0.677 | 0.041 |
| FN1 | Fibronectin | P02751-5 | 0.650 | 0.010 |
| APOA4 | Apolipoprotein A-IV | P06727 | 0.634 | 0.009 |
| PDLIM1 | PDZ and LIM domain protein 1 | O00151 | 0.624 | 0.000 |
| LCP1 | Plastin-2 | P13796 | 0.611 | 0.005 |
| TINAGL1 | Tubulointerstitial nephritis antigen-like | Q9GZM7-3 | 0.591 | 0.043 |
| TJP2 | Tight junction protein ZO-2 | Q9UDY2-5 | 0.591 | 0.000 |
| SULT2A1 | Sulfotransferase 2A1 | Q06520 | 0.588 | 0.001 |
| HMGCS2 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | P54868-2 | 0.580 | 0.009 |
| SNAP23 | Synaptosomal-associated protein 23 | O00161 | 0.563 | 0.000 |
| DSP | Desmoplakin | P15924 | 0.562 | 0.000 |
| APOB | Apolipoprotein B-100 | P04114 | 0.562 | 0.015 |
| ELOA | Elongin-A | Q14241 | 0.560 | 0.011 |
| UTP14A | U3 small nucleolar RNA-associated protein 14 homolog A | Q9BVJ6-3 | 0.536 | 0.029 |
| FKBP11 | Peptidyl-prolyl cis-trans isomerase FKBP11 | Q9NYL4-2 | 0.534 | 0.021 |
| F11R | Junctional adhesion molecule A | Q9Y624 | 0.534 | 0.001 |
| ARID3A | AT-rich interactive domain-containing protein 3A | Q99856 | 0.532 | 0.001 |
| OSBPL9 | Oxysterol-binding protein-related protein 9 | Q96SU4-7 | 0.531 | 0.001 |
| REEP6 | Receptor expression-enhancing protein 6 | Q96HR9-2 | 0.530 | 0.006 |
| ECHDC1 | Ethylmalonyl-CoA decarboxylase | Q9NTX5-2 | 0.524 | 0.007 |
| SCD | Acyl-CoA desaturase | O00767 | 0.509 | 0.001 |
| METTL7B | Methyltransferase-like protein 7B | Q6UX53 | 0.505 | 0.031 |
| DPP4 | Dipeptidyl peptidase 4 | P27487 | 0.500 | 0.031 |