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. 2021 Oct 19;11:541. doi: 10.1038/s41398-021-01664-5

Table 3.

Down-regulated GO biological processes in Scz organoids (p < 0.05).

Biological process GO:BP Term_ID Adjusted p-value Neg Log10 adjusted p
Axon Development GO:0061564 1.88E−07 6.725
Nervous System Development GO:0007399 2.98E−07 6.525
Plasma Membrane Bounded Cell Projection Organization GO:0120036 7.32E−07 6.136
Axonogenesis GO:0007409 8.26E−07 6.083
Cell Projection Organization GO:0030030 1.16E−06 5.937
Cell Morphogenesis Involved in Neuron Differentiation GO:0048667 1.29E−06 5.889
Neuron Projection Morphogenesis GO:0048812 4.63E−06 5.335
Plasma Membrane Bounded Cell Projection Morphogenesis GO:0120039 6.03E−06 5.219
Cell Projection Morphogenesis GO:0048858 6.50E−06 5.187
Cell Part Morphogenesis GO:0032990 8.89E−06 5.051
Cell Morphogenesis Involved in Differentiation GO:0000904 2.09E−05 4.680
Neuron Differentiation GO:0030182 4.18E−05 4.379
Cellular Component Morphogenesis GO:0032989 4.21E−05 4.375
Neuron Development GO:0048666 9.53E−05 4.021
Neuron Projection Development GO:0031175 0.000125503 3.901
Cell Morphogenesis GO:0000902 0.000170319 3.769
Generation of Neurons GO:0048699 0.000192896 3.715
System Development GO:0048731 0.000289587 3.538
Neurogenesis GO:0022008 0.00059592 3.225
Multicellular Organism Development GO:0007275 0.00099934 3.000
Anatomical Structure Development GO:0048856 0.002063881 2.685
Axon Guidance GO:0007411 0.002117016 2.674
Neuron Projection Guidance GO:0097485 0.002173862 2.663
Negative Regulation of Microtubule Polymerization or Depolymerization GO:0031111 0.011544881 1.938
Microtubule-Based Process GO:0007017 0.01300057 1.886
Cytoskeleton Organization GO:0007010 0.01330451 1.876
Anatomical Structure Morphogenesis GO:0009653 0.014459529 1.840
Regulation of Axon Extension GO:0030516 0.015068023 1.822
Developmental Process GO:0032502 0.01628204 1.788
Substantia Nigra Development GO:0021762 0.018211464 1.740
Microtubule Cytoskeleton Organization GO:0000226 0.023833988 1.623
Regulation of Extent of Cell Growth GO:0061387 0.027856692 1.555
Axon Extension GO:0048675 0.047873583 1.320