Table 5.
Down-regulated GO molecular functions in Scz organoids (p < 0.05).
| Molecular function | GO:MF Term_ID | Adjusted p-value | Neg Log10 adjusted p |
|---|---|---|---|
| Structural Constituent of Cytoskeleton | GO:0005200 | 0.000173652 | 3.760 |
| Cytoskeletal Protein Binding | GO:0008092 | 0.005488124 | 2.261 |
| GTPase Activity | GO:0003924 | 0.007451524 | 2.128 |
| Nucleoside-Triphosphatase Activity | GO:0017111 | 0.008195516 | 2.086 |
| Pyrophosphatase Activity | GO:0016462 | 0.020438022 | 1.690 |
| Hydrolase Activity, Acting on Acid Anhydrides, in Phosphorus-Containing Anhydrides | GO:0016818 | 0.023962071 | 1.620 |
| Hydrolase Activity, Acting on Acid Anhydrides | GO:0016817 | 0.024306171 | 1.614 |
| Tubulin Binding | GO:0015631 | 0.034081605 | 1.467 |
| GTP Binding | GO:0005525 | 0.034081605 | 1.467 |
| Microtubule Binding | GO:0008017 | 0.043893561 | 1.358 |
| Structural Molecule Activity | GO:0005198 | 0.047624863 | 1.322 |
| Guanyl Ribonucleotide Binding | GO:0032561 | 0.047641356 | 1.322 |
| Guanyl Nucleotide Binding | GO:0019001 | 0.047641356 | 1.322 |