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. 2021 Oct 19;11:20684. doi: 10.1038/s41598-021-00216-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Protein expression of key enzymes involved in arginine metabolism in kidney (A), liver (B) and heart (C) with measurements in right ventricle (RV) and left Ventricle (LV) in L-ZSF1 (white squares) and O-ZSF1 (grey squares). Y-axis shows arbitrary units that represent protein expression normalized to GAPDH (kidney/ heart) or alpha Tubulin (liver). Boxplots visualize the median, 25th and 75th percentiles and minimum/ maximum. P-values were calculated using Kruskal–Wallis test and were corrected for multiple testing using the Bonferroni-Dunn method. ^#p < 0.1, ***p < 0.001.