Table 1.

Characteristics of O-ZSF1 and L-ZSF1 at 20 weeks of age.

	L-ZSF1	O-ZSF1	p-value
Food intake (g/d)	15 ± 1.3	23 ± 1.5	< 0.0001
Body weight (g)	235 ± 9	468 ± 24	< 0.0001
Heart weight (g)	0.93 ± 0.05	1.38 ± 0.07	< 0.0001
Kidney weight (g)	0.95 ± 0.06	1.54 ± 0.11	< 0.0001
Liver weight (g)	7.20 ± 0.64	18.16 ± 1.9	< 0.0001
Tibia length (mm)	37.1 ± 1.0	37 ± 0.5	0.642
NT-proBNP (pg/ml)	895 ± 371	1200 ± 338	0.047
Glucose (mmol/L)	22.4 ± 3.1	31.2 ± 1.3	< 0.0001
LV-EF (%)	55 ± 12	63 ± 15	0.140
E/e ‘	15.0 ± 2.8	21.7 ± 3.6	< 0.001
Heart rate (bpm)	216 ± 18	214 ± 17	0.812
Heart circumference	106 ± 3	111 ± 4	0.014
LV thickness	10 ± 1.5	12 ± 1.4	0.067
Septum thickness	7.7 ± 1.2	8.9 ± 1.2	0.044
RV thickness	3.6 ± 0.5	3.3 ± 0.5	0.160

LV-EF—left ventricular ejection fraction, E/e’—ratio of mitral peak velocity of early filling (E) to early diastolic mitral annular velocity (E'), bpm—beats per minute, LV—left ventricle, RV—right ventricle, NT-proBNP—N terminal B natriuretic peptide.

Mean and standard deviation are given. P-value was calculated using Mann–Whitney-U-Test. Histological measurements are given in arbitrary units.