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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2021 Apr 20;20(4):953–955.e2. doi: 10.1016/j.cgh.2021.04.018

Table 1:

Comparison of the patient-level true positive rate at the 10% screening-level false positive rate in the overall cohort

Any-stage HCC Early-stage HCC
Any time prior to diagnosis 0–6 months prior to diagnosis Any time prior to diagnosis 0–6 months prior to diagnosis
GALAD 51.7 (95%CI: 29.–68.8) 71.4 (95% CI: 28.6–92.3) 57.9 (95% CI: 29.4–80.0) 70.0 (95%CI: 18.2–100.0)
Doylestown Plus 65.5 (95%CI: 47.6–92.6) 78.6 (95%CI: 50.0–100.0) 63.2 (95%CI: 37.5–93.8) 80.0 (95%CI: 42.9–100.0)
AFP 37.9 (95%CI: 23.3–68.2) 57.1 (95%CI: 33.3–90.0) 47.4 (95%CI: 25.0–75.0) 70.0 (95%CI: 37.5–100.0)
AFP-L3% 55.2 (95%CI: 28.1–73.1) 61.5 (95%CI: 26.7–84.6) 52.6 (95%CI: 17.6–75.0) 55.6 (95%CI: 11.7–83.3)
DCP 20.7 (95%CI: 0.0–41.4) 7.1 (95%CI: 0.0–26.7) 26.3 (95%CI: 0.0–52.6) 10.0 (95%CI: 0.0–33.3)