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. 2021 Oct 19;4:1199. doi: 10.1038/s42003-021-02717-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Smoc1^+/−;Smoc2^−/− mice were mated, and Smoc1^+/+;Smoc2^−/− and Smoc1^−/−;Smoc2^−/− littermate mice were analyzed at E17.5 macroscopically under a stereoscopic microscope (a) and by skeletal preparations stained with alizarin red and alcian blue (b–h). a Growth retardation in Smoc1^−/−;Smoc2^−/− mice. Staining in the whole body (b), skull (c), clavicle (d), scapula (e), humerus (f), tibia and fibula (g), and forelimb (h) of Smoc1^+/+;Smoc2^−/− and Smoc1^−/−;Smoc2^−/− littermate mice. a, b Scale bars: 5 mm. c–h Scale bars: 1 mm.