Table 1.

List of the 144 studied genes sub-grouped to different categories.

Groups	Gene symbol
Immunity and inflammation
Immuno-stimulation	IFNG, IL2, IL12A, IL12B, IL15, TNF
Immuno-suppression	PDL1, CSF2, CTLA4, CXCL12, CXCL5, IDO1, IL10, IL13, IL4, IL5, MIF, NOS2, PDCD1, PTGS2, TGFB1, VEGFA
Enzymatic modulators	AICDA, GZMA, GZMB, IDO1, NOS2, PTGS2
Antigen presentation	H2-D1, H2-K1
Chemokines, cytokines, growth factors, and their receptors	CCL2, CCL4, CCL5, CCL20, CCL22, CCL28, CXCL1, CXCL2, CXCL5, CXCL9, CXCL10, CXCL11, CXCL12, CCL24, CCL3, CCL7, CCL1, CCL11, CCL12, CCL17, CCL19, CCL6, CCL8, CCL9, CX3CL1, CXCL15, CXCL4, IL1A, IL1B, IL2, IL4, IL5, IL6, IL10, IL12A, IL12B, IL13, IL15, IL17A, IL22, IL23A, IL11, IL16, IL17B, IL17F, IL21, IL27, IL3, IL33, IL7, IL1RN, KITL, MIF, SPP1, TNF, TNFSF10, AIMP1, NAMPT, OSM, CSF1, CSF2, CSF3, EGF, EGFR, IGF1, TGFB1, VEGFA, CXCR7, CCR1, CCR2, CCR4, CCR5, CCR7, CCR9, CCR10, CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, IL1R1, CCR3, CCR6, CCR8, IL10RA, IL10RB, IL5RA, IL6RA, IL2RB, IL2RG, IL6ST
Signal transduction
Interferon-responsive genes	CCL2, CCL5, CXCL9, CXCL10, GBP2B, IRG1, MYD88, STAT1, TLR3, TNFSF10
NFκB targets	BCL2L1, CCL2, CCL5, CSF1, CSF2, CSF3, IFNG, TNF
STAT targets	CCL2, CCL4, CCL5, CSF1, CSF2, CSF3, CXCL9, CXCL10, CXCL11, CXCL12
Toll-like receptor (TLR) signaling	MYD88, TLR2, TLR3, TLR4, TLR7, TLR9
Apoptosis
Pro-apoptotic	FASL, TNF, TNFSF10, TRP53
Anti-apoptotic	BCL2, BCL2L1, MYC, STAT3
Tumor necrosis factor and ligand	LTA, LTB, CD40LG, TNFSF11, TNFSF13, TNFSF13B, TNFSF4, TNFRSF11B
Myokines	ACVR1B, ACVR2A, AIFM1, BMP2, BNIP3, FNDC5, FST, GABARAPL1, IGF1R, MTOR, RHEB, SMAD2, SMAD3, TGFBR1
Transcription factors	FOXP3, HIF1A, IRF1, MYC, NFκB1, STAT1, STAT3, TRP53