Table 3.
TESTEX evaluation.
| Scores | Rocca et al. (2019) | Barghi et al. (2018)§ | Bonzano et al. (2014) | Bonzano et al. (2019)§ | Boffa et al. (2020) | Stellmann et al. (2020)§ | Tavazzi et al. (2018) | Kjolhede et al. (2018)§ | Prosperini et al. (2014) | Fling et al. (2019)# | Prochazkova et al. (2020) § | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study quality | Eligibility criteria | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 |
| Randomization | 1/1 | 1/1 | 1/1 | 1/1 | 0/1 | 1/1 | 0/1 | 1/1 | 1/1 | 0/1 | 1/1 | |
| Allocation concealment | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 1/1 | 0/1 | 1/1 | 0/1 | 1/1 | 0/1 | |
| Similarity at baseline | 1/1 | 1/1 | 1/1 | 1/1 | 0/1 | 1/1 | NA/1 | 1/1 | 0/1 | 1/1 | 0/1 | |
| Blinding of assessors | 1/1 | 0/1 | 1/1° | 1/1 | 1/1° | 1/1 | 1/1 | 0/1 | 1/1° | 1/1 | 0/1% | |
| Study reporting | Outcome measures (85% patients) | 1/3 | 2/3 | 1/3 | 2/3 | 1/3 | 2/3 | 2/3 | 2/3 | 2/3 | 2/3 | 1/3 |
| Intention to treat | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 1/1 | 0/1 | 1/1 | 0/1 | 1/1 | 0/1 | |
| Between group statistical comparison | 2/2 | 1/2 | 2/2 | 1/2 | 2/2 | 2/2 | NA/2 | 2/2 | 1/2 | 2/2 | 2/2 | |
| Point measure and measure of variability | 1/1 | 0/1 | 1/1 | 0/1 | 1/1 | 0/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | |
| Activity monitoring in the control group** | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 1/1 | |
| Increased exercise intensity | 0/1 | 1/1 | 0/1 | 0/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | |
| Exercise parameters | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | 1/1 | |
| Total score | 10/15* | 8/15* | 10/15 | 9/15 | 9/15* | 12/15* | 7/15 | 12/15* | 9/15* | 12/15 | 9/15 |
NA, not applicable.
Study characteristics were retrieved from reference protocol trials or previous/pilot studies from the same group.
The point was assigned also for studies in which the physiotherapy of the control group was either delivered (as in the case of passive mobilization training), or supervised by a physiotherapist. For studies including waitlisted control groups, we awarded 1 point only if any kind of monitoring was specified (e.g., daily exercise diary).
Blinding of the MRI evaluators and MRI was listed as primary aim of the study.
Blinding of the MRI evaluators was not reported and MRI was listed as primary aim of the study.
Registered randomized controlled trial.
Points were determined based on the original registered randomized controlled trial.