Fig. 3.

Evaluation of lipid metabolism following SREBP1c silencing and OA administration

Cells were transfected with siRNA specific for SREBP1c and then treated with OA:BSA complex (0.5 mM) for 24 h to divide into following groups; i) control, ii) OA, iii) SREBP1c siRNA, iv) SREBP1c siRNA + OA. mRNA expressions of each group were measured by RT-PCR and normalized to β-actin. Relative mRNA expressions of FASN (A), SCD-1 (B) and PPARα (C).

Data are expressed as mean ± S.D.

**p < 0.01, and *p < 0.05 vs. control,

^##p < 0.01, and ^#p < 0.05 vs. OA, (n = 3).