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. 2021 Oct 6;12:743993. doi: 10.3389/fpls.2021.743993

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Copyright © 2021 Rey, Zacarias and Rodrigo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of tocopherol biosynthetic pathway in plants. Phytyl-P, phytyl phosphate; G3P, glyceraldehyde 3-phosphate; IPP, isopentenyl diphosphate; DMAPP, dimethylallyl diphosphate; GGPP, geranylgeranyl diphosphate; PPP, phytyl pyrophosphate; L-Tyr, amino acid L-tyrosine; HPP, 4-hydroxyphenylpyruvate; HGA, homogentisate; MPBQ, 2-methyl-6-phytyl-1,4-benzoquinol; DMPBQ, 2,3-dimethyl-6-phytyl-1,4-benzoquinol; VTE5, phytol kinase; VTE6, phytyl-P kinase; DXS, 1-deoxy-D-xylulose-5-phosphate synthase; GGPPS, GGPP synthase; GGDR, GGPP reductase; TAT, tyrosine aminotransferase; HPPD, HPP dioxygenase; VTE2, homogentisate phytyltransferase (HPT); VTE3, MPBQ methyltransferase (MPBQ-MT); VTE1, tocopherol cyclase (TC); VTE4, tocopherol methyltransferase (γ-TMT).