Figure 11.

(A–C) Effect of nanoparticles on the production of the cytokines TNF-α, IL-6 and lL-1β in LPS- induced RAW 264.7 macrophages. A density of 1×10⁶ cells/well of macrophages induced by LPS was seeded in 6 well plates and treated with the indicated concentrations of a flower extract and dexamethasone for 24 h. The supernatants were collected and analyzed by ELISA kits. The data are presented as the mean ± SD of three independent experiments. ^#p< 0.001, LPS–treated group vs Control, ***p< 0.001, **p< 0.01 and *p< 0.05 treated group significantly different from the LPS-treated group. Control is the basal level of cytokines released without LPS induction.