Table 1.
Demographic, biochemistry, and sleep data of all the 108 study participants.
| Cohort-1 | Cohort-2 | |||||
|---|---|---|---|---|---|---|
| PS subjects (n = 16) | OSA patients(n = 56) | p value | PS subjects (n = 8) | OSA patients (n = 28) | p value | |
| Age, years | 41.1 ± 12.8 | 43.3 ± 8.6 | 0.532 | 44.8 ± 9.3 | 50.2 ± 12.4 | 0.262 |
| Male Sex, n (%) | 14 (87.5) | 50 (89.3) | 0.376 | 6 (75) | 23 (82.1) | 0.653 |
| BMI, kg/m2 | 25.2 ± 2.9 | 25.9 ± 2.8 | 0.383 | 24.6 ± 3 | 26.6 ± 3.1 | 0.114 |
| AHI, events/hour | 3.7 ± 2.5 | 66.9 ± 12 | < 0.001 | 3.2 ± 2.6 | 57.2 ± 2.1 | < 0.001 |
| ODI, events/hour | 2.1 ± 2.2 | 55.9 ± 20.7 | < 0.001 | 1.2 ± 1.2 | 45.7 ± 25.9 | < 0.001 |
| Mean SaO2, % | 96.4 ± 1 | 93.6 ± 2.4 | < 0.001 | 95.8 ± 0.8 | 93.7 ± 2.5 | 0.003 |
| Minimum SaO2, % | 86.1 ± 10.1 | 67.5 ± 14.6 | < 0.001 | 91.2 ± 3.6 | 70.2 ± 10.7 | < 0.001 |
| Snoring index, counts/hour | 107 ± 201.5 | 377.8 ± 197.7 | < 0.001 | 66.4 ± 60.8 | 358.5 ± 174.3 | < 0.001 |
| hs CRP, mg/L | 1.79 ± 1.11 | 3.64 ± 4.73 | 0.013 | NA | NA | |
| ESS | 9.7 ± 4.1 | 10.6 ± 5.5 | 0.553 | 9.6 ± 5.7 | 10.3 ± 4.9 | 0.776 |
| EDS, n (%) | 4 (21.4) | 16 (88.9) | < 0.001 | 2 (33.3) | 10 (41.7) | 0.709 |
| Current smoking, n (%) | 6 (37.5) | 21 (44.7) | 0.616 | 2 (28.6) | 9 (32.1) | 0.856 |
| Alcoholism, n (%) | 0 (0) | 3 (6.4) | 0.3 | 0 (0) | 2 (7.1) | 0.466 |
| Cholesterol, mg/dl | 201.5 ± 42.6 | 196.3 ± 33.5 | 0.616 | 180.4 ± 37.6 | 196.2 ± 42.3 | 0.442 |
| Triglycerides, mg/dl | 166.2 ± 130.7 | 153.5 ± 86.5 | 0.566 | 131.6 ± 137.2 | 137.2 ± 89.3 | 0.9 |
| Fasting sugar, mg/dl | 100.9 ± 18.8 | 100.7 ± 11.8 | 0.944 | 98 ± 6.4 | 100.6 ± 25.5 | 0.823 |
| Hypertension, n (%) | 3 (18.8) | 18 (35.3) | 0.213 | 2 (25) | 9 (32.1) | 0.699 |
| DM, n (%) | 1 (6.3) | 2 (3.9) | 0.694 | 1 (12.5) | 4 (14.3) | 0.898 |
| Heart disease, n (%) | 1 (6.3) | 4 (7.8) | 0.832 | 0 (0) | 0 (0) | 1 |
| Stroke, n (%) | 0 (0) | 4 (7.8) | 0.248 | 1 (12.5) | 0 (0) | 0.058 |
| CKD, n (%) | 0 | 1 (1.8) | 0.59 | 0 (0) | 0 (0) | 1 |
PS primary snoring, OSA obstructive Sleep Apnea, BMI body mass index, AHI apnea hypopnea index, SaO2 arterial oxyhemoglobin saturation, ODI oxygen desaturation index, the number of dips > 4% of basal SaO2%//hour, hsCRP hypersensitivity C-reactive protein, ESS Epworth Sleepiness Scale, EDS excessive daytime sleepiness, DM diabetes mellitus, CKD chronic kidney disease.