Table 2.

Clinical trials dedicated on neuroprotection in glaucoma (from https://clinicaltrials.gov/).

Clinical trials dedicated on neuroprotection in glaucoma
Number	Study Title	Identifier	Drug/Approach	Target	Status
1	A Randomized, Sham Controlled, Masked Phase II Study to Evaluate the Safety and Efficacy of Intravitreal Implantation of NT-501 Encapsulated Cell Therapy for the Treatment of Glaucoma	NCT02862938	NT-501 encapsulated cell therapy implant	Production of ciliary neurotrophic factor	Active, not recruiting
2	A Prospective Randomized Controlled Trial of GlaucoCetin vs. Placebo in Glaucoma Patients With Visual Field Loss.	NCT04784234	GlaucoCetin	Neuroprotection	Recruiting
3	A Multicenter, Double-Masked, 2-Arm Parallel Group Study Comparing the Effect of Brimonidine 0.2% vs. Timolol 0.5% on Visual Field Stability in Patients With Low-Pressure Glaucoma	NCT00317577	Brimonidine	Neuroprotection	Completed 2004
4	Topical Brimonidine vs. Argon Laser Trabeculoplasty in Progressing Human Glaucoma. A Prospective Randomized Clinical Trial.	NCT00466479	Brimonidine	Neuroprotection	Completed 2007
5	A Phase II Study to Investigate the Safety, Efficacy, and Pharmacokinetic Profile of Twice-Daily DNB-001 in Previously Untreated Patients With Elevated Intraocular Hypertension	NCT00683501	DNB-001	Ion channel modulator	Completed 2008
6	Impact of Oral Versatile Antioxidants on Glaucoma Progression:Comparative Early Results	NCT01544192	Gingko Biloba; α-tocopherol	Neuroprotection	Completed 2012
7	Impact of Oral Versatile Antioxidants on Glaucoma Progression:Comparative Early Results	NCT01544192	Gingko Biloba; α-tocopherol	Neuroprotection	Completed 2012
8	CNTF Cell Implants For Glaucoma: A Phase I Study	NCT01408472	NT-501 encapsulated cell therapy implant	Production of ciliary neurotrophic factor	Completed 2014