Fig. 4.

Biomechanical evaluation of new subchondral bone and cartilage. A) The images of the scaffold group at 4, 12 and 24 weeks after implantation, were observed under 250x with built-in microscope of the nano-indenter. B) quantitative analysis of Young's modulus of representative the regenerative bone tissue at the center of the scaffold(a), the border of the scaffold(b), the normal trabecular tissue around the scaffold(c). C) quantitative analysis of cartilage mechanical properties with Young's modulus (MPa). ∗ p ​< ​0.05; ∗∗ p ​< ​0.01; and n.s. represents no significant difference.