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. 2021 Oct 6;12:724934. doi: 10.3389/fimmu.2021.724934

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Copyright © 2021 Yu, Zhang, Zhuo, Hong, Ye, Tang and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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WGCNA revealed gene co-expression networks in the whole peripheral blood of 169 RA patients. (A, B) Analysis of the scale-free fit index and the mean connectivity for various soft-thresholding powers; (C) Relationships of consensus modules with samples. It contains a set of highly linked genes. Each specified color represents a specific gene module; (D) Clustering dendrogram of differentially expressed genes related to RA; (E) The gene significance for RA in the turquoise module (one dot represents one gene in the turquoise module).