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Evaluation of cytokine production by CL monocytes after TLR2 and TLR4 neutralization. Monocytes from CL patients (n = 15) were treated or not with anti-TLR2 and anti-TLR4 antibodies, then infected with L. braziliensis (5:1) for 48 hours. IL-1β (A) TNF (B), IL-10 (C), CXCL9 (D) and CXCL10 (E) were quantified by ELISA. Data are representative of median cytokine production. Wilcoxon signed-rank test; *p<0.05, ** p<0.01, ***p<0.001.
