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. 2021 Oct 6;12:698947. doi: 10.3389/fgene.2021.698947

TABLE 3.

Clinical factors combined with risk factors for analysis of the overall survival of patients with gastric cancer.

Group Risk Variable Events/total (n = 368) MST (days) HR (95%CI) p Value Adjusted HR (95%CI) a Adjusted P
Tumor stage
1 Low I + II 5/23 NA 1 1
2 Low III + IV 10/31 2,100 1.291 (0.436–3.819) 0.644 1.041 (0.335–3.237) 0.945
3 High I + II 8/19 1811 1.909 (0.618–5.898) 0.261 2.165 (0.685–6.840) 0.188
4 High III + IV 22/34 406 5.004 (1.879–13.328) 0.001 5.088 (1.875–13.809) 0.001
Histologic grade
A Low G1+G2 7/16 881 1 1
B Low G3 8/38 NA 0.543 (0.197–1.498) 0.238 0.575 (0.204–1.623) 0.296
C High G1+G2 7/13 552 2.429 (0.843–6.996) 0.100 2.833 (0.971–8.267) 0.057
D High G3 23/40 474 1.938 (0.829–4.534) 0.127 2.598 (1.061–6.361) 0.037
Residual tumor
I Low R0 12/49 2,100 1 1
II Low R1+R2+RX 3/5 591 2.623 (0.733–9.388) 0.138 1.729 (0.467–6.403) 0.412
III High R0 26/48 543 3.108 (1.561–6.188) 0.001 3.486 (1.733–7.013) <0.001
IV High R1+R2+RX 4/5 262 8.239 (2.578–26.332) <0.001 10.832 (3.229–36.34) <0.001
a

Adjusted for age, tumor stage, histologic stage and residual tumor

Abbreviations: MST, median survival time; HR, hazard ratio