Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 6;11:733745. doi: 10.3389/fonc.2021.733745

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Yang, Zhou, Zeng, Zhou, Wang, Li, Zhu, Guan and Chai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Circ-0002570 competitively sponged miR-587. (A) Representative FISH images indicated subcellular location of circ-0002570 in AGS cells. (B) Intersection of miRNAs predicted by circBank and CircInteractome databases. (C) RT-PCR examined the expression of circ-0002570 in AGS cells after miR-587 or miR-935 overexpression. (D) The binding sites of circ-0002570 and miR-587. (E) Luciferase reporter assay confirmed the molecular binding. (F) Overexpression of circ-0002570 resulted in the suppression of miR-587 expression. (G) Silence of circ-0002570 promoted the expression of miR-587. (H) RIP assays determined the combination between circ-0002570 and miR-587. *p < 0.05, **p < 0.01, ***p < 0.001.