Skip to main content
. 2021 Oct 6;15:749923. doi: 10.3389/fnins.2021.749923

FIGURE 3.

FIGURE 3

Dendritic spines density decreased in serotonin transporter (SERT) knockout (KO) mice. (A) Representative photomicrographs of dendritic spines of basal dendrites in layer IV pyramidal neurons from wild-type (WT) and SERT KO mice. (B,C) Comparing the total number of apical and basal dendritic spines at a distance of per 25 μm from the cell body of layer IV pyramidal cells in WT mice with SERT KO mice, respectively. (D) Comparing the total number of dendritic spines at a distance of per 25 μm from the cell body of layer II/III interneurons in WT mice with SERT KO mice. (E–G) The dendritic spine densities of apical and basal dendrites in layer IV pyramidal neurons and in layer II/III interneurons of the auditory cortex. Data are presented as means ± SD. n = 6 for each group. * p < 0.05, *** p < 0.001, Student’s t-test and two-way ANOVA. Scale bar: 5 μm.