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. 2021 Oct 19;10(10):e1348. doi: 10.1002/cti2.1348

Figure 3.

Figure 3

PVR expression on circulating CD4+ T cells from PLWH and HIV‐seronegative controls. (a) The extent of PVR expression on CD4+ T cells from newborns (CB), HIV‐seronegative (HIVneg) adults or PLWH was measured and compared. Kruskal–Wallis test ****P < 0.0001. (b) Correlation between PVR expression on CD4+ T cells from PLWH (n = 95) and HIV‐1 disease progression (CD4 nadir) was assessed and (c) expression of PVR on CD4+ T cells from CMV‐seronegative (n = 18) or CMV‐seropositive (n = 77) PLWH contrasted. Mann–Whitney U‐test *P = 0.0290. (d) Correlation between CD4+ T‐cell TIGIT and PVR expression is depicted. Horizontal lines bisecting groups in a and c represent median with IQR.